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Differences in the efficacy of nAbs between these assays are often seen in terms of their neutralization titres measured as the concentration of nAb giving 50%, 80% or 90% inhibition of virus replication (IC 50 , IC 80 or IC 90 , respectively)
No completed Phase 2 or Phase 3 human trials have been published
Our limited patient experience shows no major difference in results between these methods
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Realworld studies demonstrate high discontinuation rates of GLP1RAs by up to 75% within the first year of use, predominantly driven by side effects 20-22
Almost always with a start-low, go-slow approach: the lowest available dose first, then gradual increases over several weeks
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